ChemicalBook CAS DataBase List 1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole

1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole synthesis

6synthesis methods

Product Name:1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole
CAS Number:165115-83-3
Molecular formula:C21H21F2N3O2
Molecular Weight:385.41

3587-60-8 Synthesis

3587-60-8
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1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole

165115-83-3
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Yield:-

Steps:

Multi-step reaction with 4 steps
1: 1.) TiCl₄; 2.) Et₃N / 1.) CH₂Cl₂, 0 deg C
2: 85 percent / LAH / tetrahydrofuran / 0 °C
3: 96 percent / I₂ / acetonitrile; pyridine / 0 - 5 °C
4: 81 percent / DMPU / dimethylformamide / 24 h / 100 °C

References:

Saksena, Anil K.;Girijavallabhan, Viyyoor M.;Wang, Haiyan;Liu, Yi-Tsung;Pike, Russell E.;Ganguly, Ashit K. [Tetrahedron Letters,1996,vol. 37,# 32,p. 5657 - 5660]

17690-16-3
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165115-83-3
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References

Benzenebutanoyl chloride, 2,4-difluoro-γ-methylene-

182009-37-6
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165115-83-3
18 suppliers
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References

165115-78-6
8 suppliers
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165115-83-3
18 suppliers
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References

2-Oxazolidinone, 3-[4-(2,4-difluorophenyl)-1-oxo-4-pentenyl]-4-(1-methylethyl)-, (S)- (9CI)

165115-71-9
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165115-83-3
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References

1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole Related Search:

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate 1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]- 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- 4-Methylbenzenesulfonhydrazide 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one (S)-[2-(Benzyloxy)propylidene]hydrazinecarboxaldehyde O-Benzyl Posaconazole 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde 4-(4-{4-[(3R,5R)-5-(2,4-DIFLUORO-PHENYL)-5-[1,2,4]TRIAZOL-1-YLMETHYL-TETRAHYDRO-FURAN-3-YLMETHOXY]-PHENYL}-PIPERAZIN-1-YL)-PHENYLAMINE

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1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole synthesis

1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole Related Search: