ChemicalBook CAS DataBase List 1-(((S)-2-(Bromomethyl)-3-methylbutoxy)methyl)benzene

1-(((S)-2-(Bromomethyl)-3-methylbutoxy)methyl)benzene synthesis

6synthesis methods

Product Name:1-(((S)-2-(Bromomethyl)-3-methylbutoxy)methyl)benzene
CAS Number:172901-00-7
Molecular formula:C13H19BrO
Molecular Weight:271.19

(S)-2-Benzyloxymethyl-3-methylbutan-1-ol

365541-75-9
6 suppliers
inquiry

1-(((S)-2-(Bromomethyl)-3-methylbutoxy)methyl)benzene

172901-00-7
39 suppliers
$155.00/1g

Yield:172901-00-7 81.1%

Reaction Conditions:

with phosphorus(V) oxybromide in N,N-dimethyl-formamide at 50; for 3 h;Temperature;Time;Solvent;

Steps:

3 Synthesis of (S)-2-(benzyloxy-methyl)-3-methyl-butyl bromide

Embodiment 3
Synthesis of (S)-2-(benzyloxy-methyl)-3-methyl-butyl bromide
Dissolve (R)-2-(benzyloxy-methyl)-3-methyl butanol (15.6 g, 75 mmol) in N,N-dimethyl formamide (246 ml), add phosphorus oxybromide (22.58 g, 78.75 mmol) in droplets slowly and control the temperature below 50° C. in that process, and then let them to react at 50° C. for 3 hours.
Cool down to room temperature, and pour the reactant liquid into water (246 ml) slowly, extract with normal hexane for three cycles, combine the normal hexane layers, wash twice with saturated sodium bicarbonate and saturated sodium chloride respectively, dry the organic layer with anhydrous sodium sulfate, filter, and condense the filtrate so as to obtain 18.1 g of oily matter.
Treat the oil matter by reduced pressure distillation to obtain 16.6 g of colorless transparent liquid; the yield is 81.1%, and the chiral purity is ≧99.9%.
¹HNMR (ppm, CDCl₃): 7.38-7.24 (m, 5H), 4.52 (s, 2H), 3.70 (dd, J=4.4 Hz, 10 Hz, 1H), 3.62 (dd, J=4.4 Hz, 9.6 Hz, 1H), 3.56 (dd, J=5.6 Hz, 10 Hz, 1H), 3.48 (dd, J=7.2 Hz, 9.6 Hz, 1H), 1.84 (m, 1H), 1.70 (s, 1H), 0.97-0.92 (m, 6H).

References:

US2013/231509,2013,A1 Location in patent:Paragraph 0024-0025

3587-60-8 Synthesis

3587-60-8
327 suppliers
$10.00/1g

172901-00-7
39 suppliers
$155.00/1g

References

(R)-3-(3-Methylbutanoyl)-4-benzyloxazolidin-2-one

145589-03-3
92 suppliers
$13.00/250mg

172901-00-7
39 suppliers
$155.00/1g

References

365541-74-8
9 suppliers
inquiry

172901-00-7
39 suppliers
$155.00/1g

References

Butanoic acid, 3-methyl-2-[(phenylmethoxy)methyl]-, (2S)-

656241-26-8
1 suppliers
inquiry

172901-00-7
39 suppliers
$155.00/1g

References

1-(((S)-2-(Bromomethyl)-3-methylbutoxy)methyl)benzene Related Search:

4-Bromomethylbenzoic acid Methyl salicylate Benzyldodecyldimethylammonium bromide Benzbromarone 3-Amino-2,2-dimethylpropionamide 4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Aliskiren inter-6 Aliskiren inter-11 2-(3-Methoxypropoxy)-4-((R)-2-(bromomethyl)-3-methylbutyl)-1-methoxybenzene BENZYL 3-BROMOPROPYL ETHER

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

1-(((S)-2-(Bromomethyl)-3-methylbutoxy)methyl)benzene synthesis

1-(((S)-2-(Bromomethyl)-3-methylbutoxy)methyl)benzene Related Search: