1-Benzyl-3-trifluoromethyl-pyrrolidine-3-carboxylic acid synthesis
1synthesis methods
- Product Name:1-Benzyl-3-trifluoromethyl-pyrrolidine-3-carboxylic acid
- CAS Number:186203-08-7
- Molecular formula:C13H14F3NO2
- Molecular Weight:273.25
Yield:186203-08-7 96%
Reaction Conditions:
with trifluoroacetic acid in dichloromethane;
References:
Fukui, Hideto;Shibata, Tetsuo;Naito, Takanobu;Nakano, Jun;Maejima, Tetsuro;Senda, Hisato;Iwatani, Wakao;Tatsumi, Yoshiyuki;Suda, Masahiro;Arika, Tadashi [Bioorganic and Medicinal Chemistry Letters,1998,vol. 8,# 20,p. 2833 - 2838]