2,3,5,6-Tetrafluoropyridine synthesis
- Product Name:2,3,5,6-Tetrafluoropyridine
- CAS Number:2875-18-5
- Molecular formula:C5HF4N
- Molecular Weight:151.06
2402-79-1
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$5.00/1g
2875-18-5
276 suppliers
$12.00/1g
Yield:2875-18-5 95%
Reaction Conditions:
with potassium fluoride in sulfolane at 120; for 6 h;Green chemistry;Reagent/catalyst;Solvent;
Steps:
5-8 Example 8: Preparation of 2,3,5,6-tetrafluoropyridine:
In a 500 mL closed four-mouth reaction bottle,43.4 g of 2,3,5,6-tetrachloropyridine prepared in Example 1 was added,58.0 g of potassium fluoride and solvent 200 mL of sulfolane,The mixture was stirred and controlled at 120 ° C for 6 hours, the reaction was completed, filtered, and the organic phase was distilled, and the fraction of 108 ° C was collected to obtain 28.7 g of 2,3,5,6-tetrafluoropyridine in a yield of 95.0%.
References:
Zhejiang University Of Technology Shangyu Institute Co., Ltd.;Fang Biao;Xu Meng;Ke Junliang CN109251167, 2019, A Location in patent:Paragraph 0013-0016
700-16-3
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2875-18-5
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$12.00/1g
3511-90-8
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$30.00/1g
2875-18-5
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$12.00/1g
617-86-7
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$9.00/5g
700-16-3
254 suppliers
$6.00/1g
2875-18-5
276 suppliers
$12.00/1g
358-43-0
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700-16-3
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1333-74-0
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$190.00/56L
3512-16-1
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2875-18-5
276 suppliers
$12.00/1g