2-AMINOPHENYLACETIC ACID synthesis
- Product Name:2-AMINOPHENYLACETIC ACID
- CAS Number:3342-78-7
- Molecular formula:C8H9NO2
- Molecular Weight:151.16
59-48-3
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3342-78-7
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Yield:-
Reaction Conditions:
Stage #1:2-oxoindole with water;sodium hydroxide at 100;
Stage #2: with hydrogenchloride in water; pH=1
Steps:
11.1
Step 1: To a suspension of indolin-2-one (5 g) in water (50 mL) was added NaOH (6.01 g). The mixture was stirred overnight at 100 °C. The pH was adjusted to 1 with concentrated hydrochloric acid to give the solution of 2-(2-aminophenyl)acetic acid in water. S(ES+) m/z 152 (ΜΙ-Γ).
References:
GLAXO GROUP LIMITED;WANG, Yonghui;YANG, Ting;LIU, Qian;XIANG, Jia-Ning WO2012/28100, 2012, A1 Location in patent:Page/Page column 27
3740-52-1
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3342-78-7
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$57.00/250mg
30095-98-8
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$25.00/1g
3342-78-7
112 suppliers
$57.00/250mg
551-93-9
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$6.00/5g
3342-78-7
112 suppliers
$57.00/250mg
56-89-3
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7732-18-5
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$12.69/100ml
611-73-4
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$36.00/5g
3342-78-7
112 suppliers
$57.00/250mg