2-Phenylimidazole synthesis
- Product Name:2-Phenylimidazole
- CAS Number:670-96-2
- Molecular formula:C9H8N2
- Molecular Weight:144.17
Yield:670-96-2 90%
Reaction Conditions:
with tribromide-modified silica-coated magnetic nanoparticles (Fe3O4/SiO2/(CH2)3N+Me3Br3) in neat (no solvent) at 80; for 0.25 h;Green chemistry;
Steps:
2.3. General procedure for the synthesis of imidazole, benzimidazole, benzothiazole, and perimidine derivatives
General procedure: A stirred solution of the substrate (1 mmol), aryl adehyde (1 mmol),and tribromide-modified silica-coated magnetic nanoparticles (Fe3O4/SiO2/(CH2)3N+Me3Br3-, 0.007 g) was heated 80 °C. After completion of the reaction [TLC (AcOEt/hexane 1:3) monitoring], EtOH (10 mL) was added. The catalyst was recovered by an external magnet, and thereaction mixture was poured into ice-water (30 mL). The solid productwas filtered, washed with ice-water, and dried.
References:
Farrokhi, Azita;Ghodrati, Keivan;Yavari, Issa [Catalysis Communications,2015,vol. 63,p. 41 - 46]
936-49-2
203 suppliers
$15.19/10g
670-96-2
463 suppliers
$6.00/10g
16265-04-6
153 suppliers
$14.00/100mg
98-80-6
747 suppliers
$5.00/5g
670-96-2
463 suppliers
$6.00/10g