2-PIPERIDYLMETHYLAMINE synthesis
- Product Name:2-PIPERIDYLMETHYLAMINE
- CAS Number:22990-77-8
- Molecular formula:C6H14N2
- Molecular Weight:114.19
100-70-9
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$13.00/25g
22990-77-8
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$27.00/5g
Yield:-
Reaction Conditions:
with ammonia;hydrogen;Ni-5584 in ethanol at 180; under 135014 Torr; for 6 h;Product distribution / selectivity;
Steps:
4
Example 4 starting from 2-cyanopyridine; A mixture of 25 g of Ni-5584 and 127.5 g of liquid ammonia was treated with 100 bar of hydrogen and heated to 180° C. After increasing the hydrogen pressure to 180 bar, 250 g of 2-cyanopyridine in 125 g of ethanol was added over the course of 6 hours. When the hydrogen absorption was complete, the system is cooled, expanded, and aerated with nitrogen, and the catalyst was filtered off. The resulting crude product had a 52% content of 2-aminomethylpiperidine.
References:
Antons, Stefan;Dreisbach, Claus US2008/188665, 2008, A1 Location in patent:Page/Page column 1
3731-51-9
346 suppliers
$5.00/5g
22990-77-8
232 suppliers
$27.00/5g