2-SALICYLIDENEAMINOPHENOL synthesis
- Product Name:2-SALICYLIDENEAMINOPHENOL
- CAS Number:1761-56-4
- Molecular formula:C13H11NO2
- Molecular Weight:213.23
Yield: 95%
Reaction Conditions:
Stage #1:2-amino-phenol in ethanol at 20;Green chemistry;
Stage #2:salicylic alcohol with oxygen in ethanol at 20; under 760.051 Torr; for 0.75 h;Catalytic behavior;Green chemistry;
Steps:
General procedure for direct preparation of Schiff base and oxime compounds catalyzed by PSA-Schiffbase-Mn(III) complex
General procedure: In an oven-dried 10-mL round-bottom flask, 10 mg catalyst 4 (3.2 mol%) along with 1 mmol amine or hydroxyl amine was added to 7 mL absolute ethanol at ambient temperature.Then, 1 mmol of alcohol was added to the reaction mixture and stirred under O2 atmosphere (~1 atm.). After 14-60 min,yellow to red sediments were appeared which show successful oxidation of alcohols followed by imine formation. The product was filtered and added to 20 mL of hot methanol which just dissolved the imine compound. The filtration of the reaction mixture left a solid on the filter that was the catalyst 4. The remained solution set a side overnight for crystallization, and the recovered catalyst was reused for the next run (Scheme 2).
References:
Kazemnejadi, Milad;Shakeri, Alireza;Mohammadi, Mohammad;Tabefam, Marzieh [Journal of the Iranian Chemical Society,2017,vol. 14,# 9,p. 1917 - 1933]
90-01-7
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1761-56-4
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