ChemicalBook CAS DataBase List 3-Bromo-2-(bromomethyl)propionic acid

3-Bromo-2-(bromomethyl)propionic acid synthesis

1synthesis methods

Product Name:3-Bromo-2-(bromomethyl)propionic acid
CAS Number:41459-42-1
Molecular formula:C4H6Br2O2
Molecular Weight:245.9

A mixture of commercially available diethyl bis(hydroxymethyl)malonate (25 g., 0.11 mol.) and a 48% aqueous hydrogen bromide solution (192 cm3, 1.70 mol) was heated until the ethyl bromide liquid began to evaporate from the mixture and then vigorously di

20605-01-0 Synthesis

20605-01-0
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$6.00/5g

41459-42-1
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$6.00/1g

Yield:41459-42-1 85%

Reaction Conditions:

with hydrogen bromide

References:

Mondal, Dibyendu;Koehn, Eric M.;Yao, Jiajun;Wiemer, David F.;Kohen, Amnon [Bioorganic and Medicinal Chemistry,2018,vol. 26,# 9,p. 2365 - 2371]

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3-Bromo-2-(bromomethyl)propionic acid synthesis

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