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ChemicalBook CAS DataBase List 3-METHYL-5-PHENYLPYRIDINE
10477-94-8

3-METHYL-5-PHENYLPYRIDINE synthesis

14synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / tetrahydrofuran / 20 °C / Sealed tube; Inert atmosphere
2: bis(1,5-cyclooctadiene)nickel (0); 1,3-bis-(diphenylphosphino)propane; methanol / 3 h / 80 °C / Glovebox; Inert atmosphere
3: diisobutylaluminium hydride / toluene / 2.5 h / -78 °C

References:

Fang, Xianjie;Gao, Jihui;Sun, Feilong [Chemical Communications,2020,vol. 56,# 50,p. 6858 - 6861]

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