[1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide synthesis
1synthesis methods
- Product Name:[1-(Ethoxycarbonyl)ethyl]triphenylphosphonium bromide
- CAS Number:30018-16-7
- Molecular formula:C23H24BrO2P
- Molecular Weight:443.32
603-35-0
535-11-5
30018-16-7
1.0 g of triphenylphosphine was dissolved in 15 mL of ethyl acetate and 0.55 mL of ethyl 2-bromopropionate was added to this solution. The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the bulk of the resulting white solid product was collected by diafiltration. The solids were washed with ethyl acetate to give a final 1.35 g of white solid product ethoxycarbonyl ethyltriphenylphosphonium bromide in 80.5% yield.
Yield:-
Reaction Conditions:
in chloroformReflux;
References:
Xu, Shibo;Li, Chunju;Jia, Xueshun;Li, Jian [Journal of Organic Chemistry,2014,vol. 79,# 22,p. 11161 - 11169]