Ethyl acetate synthesis
- Product Name:Ethyl acetate
- CAS Number:141-78-6
- Molecular formula:C4H8O2
- Molecular Weight:88.11
Ethyl acetate is a colorless liquid has a characteristic sweet smell (similar to pear drops) and is used in glues, nail polish removers, and in the decaffeination process of tea and coffee.
Ethyl acetate is synthesized in industry mainly via the classic Fischer esterification reaction of ethanol and acetic acid. This mixture converts to the ester in about 65% yield at room temperature:
CH3CO2H + CH3CH2OH → CH3CO2CH2CH3 + H2O
75-07-0
431 suppliers
$14.00/5mL
141-78-6
724 suppliers
$22.37/250ml
Yield:141-78-6 95%
Reaction Conditions:
with [{(PhN)MeC(Nt-Bu)}AlMe(μ-OMe)]2 at 20; for 16 h;Inert atmosphere;Schlenk technique;Green chemistry;Tishchenko-Claisen Dismutation;
Steps:
2.5 General procedure employed for the Tishchenko reaction
General procedure: The pre-catalyst, amidinatoaluminum compound (0.8 mmol) was placed in a dry Schlenk flask under a nitrogen atmosphere, and freshly distilled aldehyde (80 mmol) was introduced. The mixture was immediately stirred at room temperature for 30 min to produce the corresponding ester. The reaction was quenched with 0.5 ml of water and the product was distilled to collect the corresponding ester. The yields reported are the isolated yield.
References:
Zhang, Shaofeng;Han, Hongfei;Guo, Zhiqiang;Tong, Hongbo;Wei, Xuehong [Polyhedron,2015,vol. 90,p. 118 - 122]
64-17-5
857 suppliers
$10.00/50g
64-19-7
1680 suppliers
$10.00/25ML
141-78-6
724 suppliers
$22.37/250ml
64-17-5
857 suppliers
$10.00/50g
75-07-0
431 suppliers
$14.00/5mL
64-19-7
1680 suppliers
$10.00/25ML
141-78-6
724 suppliers
$22.37/250ml
64-17-5
857 suppliers
$10.00/50g
75-07-0
431 suppliers
$14.00/5mL
141-78-6
724 suppliers
$22.37/250ml