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4,7-DICHLORO-2,8-DIMETHYLQUINOLINE synthesis

2synthesis methods

87-60-5 Synthesis

Yield:-

Steps:

Multi-step reaction with 3 steps
1: methanol / 7 h / 40 °C
2: diphenylether / 0.5 h / Reflux
3: trichlorophosphate / 3 h / Reflux

References:

Luo, Wei;Liu, Yang;Wang, Jian;Guo, Chun;Lu, Wei-Qiang;Cui, Kun-Qiang [Medicinal Chemistry Research,2012,vol. 21,# 10,p. 3073 - 3079,7]

21629-48-1 Synthesis

7-Chloro-2-methylquinoline 4,7-Dichloroquinoline 2,8-Dimethylquinoline 4,7-DICHLORO-8-METHYLQUINOLINE

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