4-HYDROXY-8-METHYLQUINOLINE synthesis
- Product Name:4-HYDROXY-8-METHYLQUINOLINE
- CAS Number:23432-44-2
- Molecular formula:C10H9NO
- Molecular Weight:159.18
35966-17-7
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23432-44-2
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Yield:23432-44-2 91.6%
Reaction Conditions:
in diphenylether at 240 - 260; for 0.666667 h;
Steps:
21.D Step D: Preparation of 4-hydroxy-8-methylquinoline
Take 4-hydroxy-8-methylquinoline-3-carboxylic acid 2.23g (0.011mol) in a 250ml trineck bottle, add 50ml diphenyl ether, react at 240 °C to 260 °C for 40min, stop heating, cool to room temperature and add 50ml of petroleum ether, filter, wash petroleum ether twice, give 4-hydroxy-8-methylquinoline white solid 1.60g, yield 91.60%; M.p.: 204.6~205.2 °C; ESI-MS(m/z). ):160.01([M+H]+),182.02([M+Na]+),158.05([M-H]-)
References:
CN114751858,2022,A Location in patent:Paragraph 0125; 0131-0132
77156-75-3
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23432-44-2
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19146-73-7
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95-53-4
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23432-44-2
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![2,2-dimethyl-5-[(2-methylanilino)methylidene]-1,3-dioxane-4,6-dione](/CAS/20180720/GIF/25253-09-2.gif)
25253-09-2
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23432-44-2
77 suppliers
$16.00/100mg