4-(2-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER synthesis
- Product Name:4-(2-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- CAS Number:494773-35-2
- Molecular formula:C15H21BrN2O2
- Molecular Weight:341.24
1011-13-8
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24424-99-5
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494773-35-2
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$16.00/100 mg
Yield: 91%
Reaction Conditions:
in ethanol at 30;
Steps:
2
The above solid was dissolved in 100 ml of absolute ethanol, and Boc2O13.1g (0.06mo1) was added, and the mixture was stirred at 30 ° C until the reaction was completed, concentrated to dryness under reduced pressure, and crystallized from n-hexane-ethyl acetate to obtain4- (2-Bromophenyl) piperazine-1-carboxylic acid tert-butyl ester18.6g, yield 91%.
References:
Jiangsu Haosen Pharmaceutical Group Co., Ltd.;Cao Jin;You Junhui;Du Zuyin;Zhao Junjun;Qi Gaofei CN104829558, 2020, B Location in patent:Paragraph 0066; 0067; 0070; 0071
57260-71-6
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583-53-9
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494773-35-2
79 suppliers
$16.00/100 mg
583-55-1
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$7.00/5g
57260-71-6
723 suppliers
$5.00/5g
494773-35-2
79 suppliers
$16.00/100 mg
170017-74-0
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$19.00/250mg
494773-35-2
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$16.00/100 mg
583-55-1
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50606-33-2
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75-65-0
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494773-35-2
79 suppliers
$16.00/100 mg
1011-13-8
136 suppliers
$45.00/25mg