5-Bromopentan-1-ol synthesis
- Product Name:5-Bromopentan-1-ol
- CAS Number:34626-51-2
- Molecular formula:C5H11BrO
- Molecular Weight:167.04
111-29-5
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$5.00/25g
34626-51-2
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$13.43/250mgs:
Yield:34626-51-2 89.1%
Reaction Conditions:
with hydrogen bromide in benzene at 70 - 80; for 15 h;
Steps:
1.1 Preparation of 5-bromo-1-pentanol (2a)
In 250mL three-necked flask add 1a (14 g, 0.135 mol), 40% hydrobromic acid (28 mL, 0.2 mol) and 60 mL of benzene, 70 ~ 80 ° C oil bath water for 15h, TLC detection, raw material points disappear. Washed successively with 5% sodium hydroxide solution, 10% hydrochloric acid and saturated brine, and dried over anhydrous sodium sulfate. The crude product was separated by silica gel column chromatography (petroleum ether: ethyl acetate, V / V = 8: 1) and concentrated to give colorless to pale yellow liquid 2a (20.1g, yield 89.1%).
References:
Northwest A&F University;Tang, Guanghui;Zhang, Tao;Wei, Cong;Zhang, Jing;Cai, ChongLin CN105766907, 2016, A Location in patent:Paragraph 0026; 0041; 0042
142-68-7
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34626-51-2
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15848-22-3
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34626-51-2
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2067-33-6
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34626-51-2
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14660-52-7
252 suppliers
$6.00/5g
34626-51-2
182 suppliers
$13.43/250mgs: