5-BROMOPROTOCATECHUALDEHYDE synthesis
- Product Name:5-BROMOPROTOCATECHUALDEHYDE
- CAS Number:16414-34-9
- Molecular formula:C7H5BrO3
- Molecular Weight:217.02
2973-76-4
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16414-34-9
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Yield: 100%
Reaction Conditions:
Stage #1:5-bromo-4-hydroxy-3-methoxybenzaldehyde with boron tribromide in dichloromethane at 0 - 20; for 2.83333 h;
Stage #2: with methanol in dichloromethane at 0;
Steps:
31.b
(b) 3-Bromo-4,5-dihydroxybenzaldehydeTo a solution of 3-bromo-4-hydroxy-5-rnethoxybenzaldehyde (12. Ig, 0.52 mol) in dichloromethane (200 ml) was added 1.0 M boron tribromide in dichloromethane (2.2 eq, 115 ml) at 0°. The reaction was stirred at 0° for 20 min, then at ambient temperature for 2.5h. The reaction was then cooled to 0°, and quenched by the slow addition of
References:
GLAXO GROUP LIMITED WO2007/122258, 2007, A1 Location in patent:Page/Page column 44-45
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16414-34-9
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121-33-5
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16414-34-9
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$45.00/50mg
621-59-0
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16414-34-9
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