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ChemicalBook CAS DataBase List (3a,5b,7a,12b)-3,7,12-trihydroxy-Cholan-24-oic acid
71883-64-2

(3a,5b,7a,12b)-3,7,12-trihydroxy-Cholan-24-oic acid synthesis

6synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: methyl 3α,7α-diacetoxy-12-oxo-5β-cholan-24-oatewith sodium tetrahydroborate;cerium(III) chloride heptahydrate in tetrahydrofuran;methanol at 0;
Stage #2: with methanol;potassium hydroxide at 80;Reagent/catalyst;

References:

Luxenburger, Andreas;Clemmens, Hannah;Hastings, Christopher;Harris, Lawrence D.;Ure, Elizabeth M.;Cameron, Scott A.;Aasly, Jan;Bandmann, Oliver;Weymouth-Wilson, Alex;Furneaux, Richard H.;Mortiboys, Heather [Biomolecules,2023,vol. 13,# 1,art. no. 76]

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