Azelaic acid synthesis
- Product Name:Azelaic acid
- CAS Number:123-99-9
- Molecular formula:C9H16O4
- Molecular Weight:188.22
112-80-1
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123-99-9
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Yield:123-99-9 99.23%
Reaction Conditions:
with phosphotungstic acid;potassium permanganate;N-benzyl-N,N,N-triethylammonium chloride;dihydrogen peroxide;oxygen at 95; for 8 h;Reagent/catalyst;Concentration;Temperature;
Steps:
4
In a 500-mL four-necked flask equipped with an electromagnetic stirrer, a thermometer and a condenser, 50 g of oleic acid, 5 g of phosphotungstic acid catalyst, 3 g of benzyltriethylammonium chloride was added, and the flow rate of oxygen 20g / L.Rapidly heated to 95 ° C, adding 2 g of potassium permanganate, adding 200 ml of hydrogen peroxide at a mass concentration of 30% to react for 8 hours. After the reaction, the mixture was placed in a separatory funnel for separation, Manganese in the lower part of the water layer, the oil layer in the above, easy to separate.The separated aqueous phase was crystallized at 0 to 5 ° C and the manganese dioxide was washed three times with 300 ml of boiling water. The resulting liquid was concentrated to 50 mL at 100 ° C and cooled at 0 to 5 ° C to precipitate a white powder. Two parts of the liquid filter, dry, was azelaic acid, the calculated yield of about 99.23%.
References:
CN104447279,2016,B Location in patent:Paragraph 0017-0018
141-22-0
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123-99-9
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123-99-9
796 suppliers
$14.00/5g