CO-1686 synthesis

8synthesis methods

Product Name:CO-1686
CAS Number:1374640-70-6
Molecular formula:C27H28F3N7O3
Molecular Weight:555.55

5-Fluoro-2-nitroanisole was condensed with piperazine, acetylated and reduced to give 1-(3-methoxy-4-aminophenyl)-4-acetylpiperazine (4); and 2,4-dichloro-5-trifluoromethylpyrimidine was condensed with 3-nitroaniline, reduced, and amidated to give N-[3-(2

3932-97-6 Synthesis

2,4-Dichloro-5-trifluoromethylpyrimidine

3932-97-6
329 suppliers
$6.00/250mg

1374640-70-6
197 suppliers
$50.00/5mg

Yield:-

Steps:

Multi-step reaction with 5 steps
1: N-ethyl-N,N-diisopropylamine / butan-1-ol / 5 h / 0 - 20 °C
2: trifluoroacetic acid / dichloromethane / 0 - 20 °C
3: N-ethyl-N,N-diisopropylamine / dichloromethane / -30 - 20 °C
4: 1,4-dioxane / 50 °C
5: sodium carbonate / dichloromethane / 0.58 h / 0 - 20 °C

References:

CELGENE AVILOMICS RESEARCH, INC.;LAI, Mei WO2013/138495, 2013, A1

tert-butyl (3-((2-chloro-5-(trifluoroMethyl)pyriMidin-4-yl)aMino)phenyl)carbaMate

1374507-23-9
40 suppliers
inquiry

1374640-70-6
197 suppliers
$50.00/5mg

References

1-(4-(4-aMino-3-Methoxyphenyl)piperazin-1-yl)ethanone

1021426-42-5
99 suppliers
$38.00/1G

1374640-70-6
197 suppliers
$50.00/5mg

References

68621-88-5 Synthesis

68621-88-5
204 suppliers
$6.00/1g

1374640-70-6
197 suppliers
$50.00/5mg

References

N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine

1374507-24-0
17 suppliers
inquiry

1374640-70-6
197 suppliers
$50.00/5mg

References

CO-1686 Related Search:

AZD-9291 Poziotinib (HM781-36B) Neratinib Tucatinib Anlotinib Olmutinib Savolitinib

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

CO-1686 synthesis

CO-1686 Related Search: