Coumarin 334 synthesis
- Product Name:Coumarin 334
- CAS Number:55804-67-6
- Molecular formula:C17H17NO3
- Molecular Weight:283.32
63149-33-7
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141-97-9
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55804-67-6
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$59.70/500mg
Yield: 79%
Reaction Conditions:
with piperidine in ethanol for 6 h;Reflux;
Steps:
1 Synthesis of coumarin derivatives represented by formula (III)
The 8-hydroxy-nonalonidine-9-carbaldehyde (0.6518g, 3mmol), ethyl acetate (0.7748g, 3mmol) and piperidine (0.5ml, 3mmol) represented by formula (II) were dissolved in 24mL of anhydrous In ethanol.The mixture was heated and refluxed for 6 hours, then cooled to room temperature.The suspension was then collected by filtration and washed with cold absolute ethanol.Finally, the product was dried under vacuum to obtain orange crystals, and the coumarin derivative represented by formula (III) (0.6715 g, 79%) was obtained.
References:
Zhou Xuejun;Xu Zhencai;Wang Xiaofeng;Zou Yuxia;Duan Tingting;He Rong;Wang Fangwu;Qin Jidong CN112010865, 2020, A Location in patent:Paragraph 0009; 0035-0038
41175-50-2
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55804-67-6
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591-27-5
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55804-67-6
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536-90-3
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55804-67-6
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63468-83-7
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55804-67-6
89 suppliers
$59.70/500mg