DIDECYLAMINE synthesis
- Product Name:DIDECYLAMINE
- CAS Number:1120-49-6
- Molecular formula:C20H43N
- Molecular Weight:297.56
Yield:1120-49-6 35%
Reaction Conditions:
with potassium carbonate in dimethyl sulfoxide at 80; for 12 h;
Steps:
5.3.1.1. Synthesis of N,N-di-n-hexylamine (i)a
General procedure: Mixture of n-hexylamine (2 g, 19.6 mmol), n-hexyl bromide (3.17 g, 19.6 mmol) and anhydrous potassium carbonate (1.99 g, 19.6 mmol) in 15 mL dimethyl sulfoxide was kept under stirring for 12 h at 80oC. The reaction mixture was taken in 50 mL chloroform, washed with water (3 x 50 mL), dried over anhydrous magnesium sulfate and filtered. Chloroform was removed from the filtrate on a rotary evaporator. Silica gel column chromatographic purification of the resulting residue using 60-120 mesh silica gel size and 1-2% methanol in chloroform (v/v) as the eluent, afforded the intermediate secondary amine. This yielded compound (i)a as a Yellow liquid (1.2 g, 32% yield, Rf =0.6 in 10% methanolic chloroform, v/v,as the TLC developing solvent).
References:
Sudhakar, Godeshala;Bathula, Surendar Reddy;Banerjee, Rajkumar [European Journal of Medicinal Chemistry,2014,vol. 86,p. 653 - 663]
2016-57-1
235 suppliers
$6.00/1g
1120-49-6
157 suppliers
$31.00/5g
1002-69-3
239 suppliers
$7.00/25g
1120-49-6
157 suppliers
$31.00/5g
1975-78-6
110 suppliers
$7.00/5g
1120-49-6
157 suppliers
$31.00/5g
124-22-1
424 suppliers
$5.00/25g
1120-49-6
157 suppliers
$31.00/5g