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ChemicalBook CAS DataBase List Endosulfan I
959-98-8

Endosulfan I synthesis

1synthesis methods
Alpha-endosulfan is produced via a multi-step synthesis involving Diels-Alder cycloaddition followed by chlorination and sulphite ester formation. The process yields two stereoisomers: alpha- and beta-endosulfan, with the alpha form being more biologically active. Isolation of the alpha-isomer from the beta-isomer is achieved through fractional crystallisation, exploiting differences in their melting points and solubility.
-

Yield:-

Reaction Conditions:

with thionyl chloride

References:

Farbw. Hoechst DE1015797, 1954, B

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