Ethyl 2-(2-cyanophenoxy)acetate ,96% synthesis
1synthesis methods
- Product Name:Ethyl 2-(2-cyanophenoxy)acetate ,96%
- CAS Number:39786-34-0
- Molecular formula:C11H11NO3
- Molecular Weight:205.21
Yield:39786-34-0 96.7%
Reaction Conditions:
with potassium carbonate in acetone at 60; for 12 h;
Steps:
1.1 Synthesis of intermediate product (L-1)
In a 3000 mL flask, 87.0 g (730 mmol) of 2-cyanophenol, 124.4 g (745 mmol) of ethyl bromoacetate, 403.8 g (2.92 mol) of potassium carbonate and 1740 mL of acetone were placed and reacted at 60 DEG C for 12 hours. The reaction was terminated by TLC and then cooled to room temperature, filtered and washed with water and acetone to obtain 150 g (yield: 96.7%) of intermediate L-1.
References:
KR2015/17817,2015,A Location in patent:Paragraph 0101-0104