2-Cyanophenol synthesis
- Product Name:2-Cyanophenol
- CAS Number:611-20-1
- Molecular formula:C7H5NO
- Molecular Weight:119.12
65-45-2
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611-20-1
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Yield:611-20-1 98.8%
Reaction Conditions:
with phosgene;L-lysine in 1,2-dichloro-ethane at 80; for 4 h;Reagent/catalyst;Temperature;
Steps:
3 Example 3: Synthesis of o-hydroxybenzonitrile
To the reaction flask, 138.5 g (1.0 mol) of o-hydroxybenzamide,0.028 g of lysine, 700 g of dichloroethane,Warmed to 80 C, began to pass phosgene,3h access108.8 g (1.1 mol),Insulation reaction 1h;After completion of the reaction, about 350 g of ethylene dichloride was distilled off,Stop distillation, ice bath cooling, a crystalPrecipitation, continue stirring, down to 0 ° C, stirring 1h, filtered,Dried to give 118.8g,Content of 99.1%Yield 98.8% (Calculated as o-hydroxybenzamide).
References:
CN104610095,2016,B Location in patent:Page/Page column 4; 5
138642-62-3
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611-20-1
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90-02-8
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611-20-1
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873-32-5
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611-20-1
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2042-37-7
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611-20-1
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