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ChemicalBook CAS DataBase List Sodium salicylate
54-21-7

Sodium salicylate synthesis

9synthesis methods
30 g of sodium hydroxide is dissolved in 300 ml of water, to which 100 g of salicycilic acid is then added with agitation. The agitation is continued for a while to dissolve the salicylic acid completely and then the solution is evaporated to dryness to obtain 110 g of sodium salicylate.Sodium salicylate synthesis
-

Yield:-

Reaction Conditions:

with sodium hydroxide in toluene at 140 - 150; under 4500.45 - 6000.6 Torr; for 1 h;

Steps:

1-3

The vaporized carbon dioxide gas is continuously introduced into the toluene suspension of sodium phenate to carry out the carboxylation reaction. During the reaction, the temperature of the kettle is controlled to be 140150, and the pressure is 0.6Mpa0.8Mpa. When the pressure of the kettle no longer drops, stop Carbon dioxide was passed through, the pressure was maintained for 1 hour, the reaction was terminated, the temperature was lowered, and nitrogen was replaced to obtain a toluene suspension of sodium salicylate.

References:

CN112341335,2021,A Location in patent:Paragraph 0016-0017; 0020-0021; 0024-0025

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