4-Nitrobenzonitrile synthesis
- Product Name:4-Nitrobenzonitrile
- CAS Number:619-72-7
- Molecular formula:C7H4N2O2
- Molecular Weight:148.12
619-73-8
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$5.00/10g
619-72-7
383 suppliers
$11.00/1g
Yield:619-72-7 99%
Reaction Conditions:
Stage #1: 4-Nitrobenzyl alcoholwith 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical;iodine in dichloromethane at 20; for 2 h;
Stage #2: with ammonium hydroxide in dichloromethane at 20; for 2 h;Reagent/catalyst;
Steps:
16
General procedure: With respect to 2 mmol of each alcohol represented by the general formula (1), 4 ml of CH 2 Cl 2 as a solvent, 0.05 equivalent of TEMPO as an N-nitrosyl compound, (A) t-BuOCl, (B) I 2 or (C ) N, N'-diiodo-5,5-dimethylhydantoin (DIH) were mixed in a predetermined amount and stirred for a predetermined time at room temperature.Next, 1.5 equivalents of I 2 and 4 ml of aqueous ammonia were added, and the mixture was stirred at room temperature for 2 hours.
References:
JP2015/40203,2015,A Location in patent:Paragraph 0041-0043; 0045
1129-37-9
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619-72-7
383 suppliers
$11.00/1g
17271-88-4
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619-72-7
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104-03-0
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619-72-7
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$11.00/1g
7291-01-2
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619-72-7
383 suppliers
$11.00/1g