3-Nitrobenzonitrile synthesis
- Product Name:3-Nitrobenzonitrile
- CAS Number:619-24-9
- Molecular formula:C7H4N2O2
- Molecular Weight:148.12
99-61-6
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619-24-9
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Yield:619-24-9 99%
Reaction Conditions:
with ammonia;iodine in water;acetonitrile at 20; for 0.666667 h;
Steps:
2 Example 2
Order of addition: In 100 mL round-bottom flask, 0.153 g between nitrobenzaldehyde dissolved in acetonitrile, the addition of I2 to the reaction system, the reaction system was reddish brown. After addition of aqueous ammonia followed by 0.8 mL, room temperature, while stirring the reaction 10 min, gusset to test whether the reaction was complete. Aqueous ammonia was added 0.8 mL, half an hour the reaction, the reaction system was orange-red, continuously adding ammonia to the reaction system until the completion of the reaction by TLC, was added Na2S203 (sodium thiosulfate) removal of excess I2 (iodine) was added to a round bottom flask , pure water was added, extracted with ethyl acetate, then the product Na2S04 (anhydrous sodium sulfate) as desiccant, the final spin-drying the solvent with a rotary evaporator apparatus, to give the product, yield 99%.
References:
CN107382771,2017,A Location in patent:Paragraph 0018
619-25-0
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619-24-9
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100-47-0
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619-24-9
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619-24-9
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619-24-9
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