3-Bromobenzonitrile synthesis
- Product Name:3-Bromobenzonitrile
- CAS Number:6952-59-6
- Molecular formula:C7H4BrN
- Molecular Weight:182.02
3132-99-8
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6952-59-6
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Yield:6952-59-6 89%
Reaction Conditions:
with ammonium acetate;phenyltrimethylammonium tribromide in acetonitrile at 20; for 16 h;
Steps:
General procedure: to a solution of 2-pyridinecarbaldehyde 1 (54 mg, 0.5 mmol) and ammonium acetate (385mg, 5.0 mmol) in MeCN )6ml), was added trimethylphenylammonium tribromide (376 mg, 1.0 mmol) at room temperature. after stirring for 21 h at rt, the reaction mixture was treated with 0.5 M aq Na2S2O3(10 ml), 1.0 M NaHCO3 )15 ml) and extracted with EtOAc (60 mL). The organic layer was washed with 0.5 M Na2S2O3 and successively washed with saturated aq.NaCl, and dried over MgSO4.
References:
Sayama, Shinsei [Heterocycles,2016,vol. 92,# 10,p. 1796 - 1802]
15852-73-0
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6952-59-6
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591-17-3
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6952-59-6
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2039-86-3
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$15.00/1g
6952-59-6
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126799-86-8
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6952-59-6
365 suppliers
$9.00/10g