Faropenem sodium synthesis
- Product Name:Faropenem sodium
- CAS Number:122547-49-3
- Molecular formula:C12H14NO5S.Na
- Molecular Weight:307.3
106560-14-9
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122547-49-3
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$6.00/5mg
Yield:122547-49-3 125 g
Reaction Conditions:
with sodium 2-ethylhexanoic acid in tetrahydrofuran;water at 20; for 2 h;
Steps:
5 Example 5
The concentrated product obtained in the above was dissolved in 600 ml of tetrahydrofuran, and a mixed solution of 100.0 g of sodium 2-ethylhexanoate in tetrahydrofuran (200 ml) and water (200 ml) was added and stirred at room temperature for 2 h. A light yellow solid was formed, filtered, and the crude product of faroconin sodium was 147.0g.;_Example 6;_The solid was dissolved in deionized water (2200 ml) at room temperature and acetone was slowly added with stirring until the solution began to become cloudy. When about 750 ml of acetone was added. The solution began to become turbid, stop adding, continue to stir the crystal overnight, pumping, acetone washing, drying, to be white faropernan sodium boutique 125.0g.
References:
Jiangsu Zhengda Qingjiang Pharmaceutical Co., Ltd.;Wang Wuwei;Chen Jie;Gu Haicheng;Wang Wei CN103880864, 2017, B Location in patent:Paragraph 0015; 0038; 0039; 0040; 0041
106559-80-2
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122547-49-3
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106560-32-1
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122547-49-3
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120705-67-1
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122547-49-3
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429691-43-0
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122547-49-3
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