Methotrexate α-tert-Butyl Ester synthesis
- Product Name:Methotrexate α-tert-Butyl Ester
- CAS Number:79640-70-3
- Molecular formula:C24H30N8O5
- Molecular Weight:510.55
45120-30-7
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![4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID](/CAS/GIF/19741-14-1.gif)
19741-14-1
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Yield:79640-70-3 91%
Reaction Conditions:
with benzotriazole-1-yl-oxy-tris(dimethylamino)phosphonium hexafluorophosphate;N-ethyl-N,N-diisopropylamine in (methylsulfinyl)methane;
References:
Goonewardena, Sascha N.;Kratz, Jeremy D.;Zong, Hong;Desai, Ankur M.;Tang, Shengzhuang;Emery, Sarah;Baker Jr., James R.;Huang, Baohua [Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,# 10,p. 2872 - 2875] Location in patent:supporting information
79640-72-5
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19741-14-1
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79640-70-3
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![L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-(1,1-dimethylethyl) 5-methyl ester](/CAS/20210305/GIF/79648-88-7.gif)
79648-88-7
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79640-70-3
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79640-72-5
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79640-70-3
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![Benzoic acid,4-[methyl[(phenylmethoxy)carbonyl]amino]-](/CAS/20180601/GIF/2528-30-5.gif)
2528-30-5
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79640-70-3
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