ChemicalBook CAS DataBase List METHYL 2-METHOXYPROPIONATE

METHYL 2-METHOXYPROPIONATE synthesis

9synthesis methods

Product Name:METHYL 2-METHOXYPROPIONATE
CAS Number:17639-76-8
Molecular formula:C5H10O3
Molecular Weight:118.13

Methyl 2-methoxypropionate is prepared by esterification of the known O-methyllactic acid.

67-56-1 Synthesis

67-56-1
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547-64-8
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$15.00/5 mL

17639-76-8
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$37.39/5g

Yield:17639-76-8 91.7%

Reaction Conditions:

5% by weight NaH2PO4/SiO2 at 260; for 60 h;Product distribution / selectivity;Gas phase;

Steps:

1
EXAMPLE 1; [0010] 30 g of the catalyst - 5% by weight NaH₂Pθ4/Siθ2 - was charged into a stainless steel tubular reactor, having a volume of 50 cm³. The temperature of the catalytic layer was maintained at 26O⁰C.[0011] 20 g/h mixture of methyl lactate with a concentration of 50% in methanol was vaporized through a preheating layer and supplied into the catalytic layer. The products of the reaction was condensed and analyzed. A conversion of methyl lactate was 94%, selectivity to methyl 2- methoxypropionate was 98%, the yield of methyl 2-methoxypropionate was 92%. Even in 60 hours after starting the reaction, the yield of methyl 2-methoxypropionate was 91.7%.

References:

NORDBIOCHEM Oü WO2008/98580, 2008, A1 Location in patent:Page/Page column 2

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5445-17-0 Synthesis