N-2-fluorenylbenzamide synthesis
3synthesis methods
- Product Name:N-2-fluorenylbenzamide
- CAS Number:3671-78-1
- Molecular formula:C20H15NO
- Molecular Weight:285.34
Yield:3671-78-1 39%
Reaction Conditions:
Stage #1: 2-nitro-9H-fluorene;benzoic acid ethyl esterwith chromium chloride;chloro-trimethyl-silane;magnesium;4,4'-di-tert-butyl-2,2'-bipyridine in tetrahydrofuran at 90; for 12 h;Schlenk technique;Inert atmosphere;
Stage #2: with hydrogenchloride;water in tetrahydrofuran;
References:
Ling, Liang;Chen, Changpeng;Luo, Meiming;Zeng, Xiaoming [Organic Letters,2019] Location in patent:supporting information
