一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

2918-77-6

N-(4-CHLOROPHENYL) METHACRYLAMIDE synthesis

6synthesis methods
-

Yield:2918-77-6 71.2 %

Reaction Conditions:

with phosphorus pentoxide;4-hydroxy-2,2,6,6-tetramethylpiperidine oxide in 1-methyl-pyrrolidin-2-one at 125;Inert atmosphere;Temperature;Solvent;

Steps:

5; 12; 33 [Example 33]

In a 30 mL test tube, 5.0 mg of 4-hydroxy TEMPO, 1.0 g (7.84 mmol, 1.0 eq.) of 4-chloroaniline, 1.18 g (13.72 mmol, 1.75 eq.) of methacrylic acid, 2.0 mL of N-methylpyrrolidone (NMP) was added as a solvent and mixed. After the inside of the test tube was replaced with nitrogen, 0.80 g (5.49 mmol, 0.7 eq.) of phosphorus pentoxide was added, and the mixture was heated and stirred at 125° C. for 4 hours. After the reaction was completed, 10 mg of the resulting reaction solution was diluted with 10 mL of a mixed solvent of acetonitrile/dimethylsulfoxide=9/1 by volume, and analyzed by high performance liquid chromatography. As a result, the area % of the target 1,2-adduct was 71.20%, and the area % of the by-product 1,4-adduct was 2.02%.

References:

WO2022/249994,2022,A1 Location in patent:Paragraph 0087-0088; 0098-0099; 0142-0143

N-(4-CHLOROPHENYL) METHACRYLAMIDE Related Search:

开原市| 云林县| 祥云县| 思茅市| 福鼎市| 清苑县| 台前县| 清徐县| 永嘉县| 田林县| 凤阳县| 恩施市| 新竹市| 桃园市| 武山县| 澄迈县| 金秀| 乌审旗| 阜宁县| 辽源市| 永定县| 娄底市| 乌拉特中旗| 香港 | 松桃| 文安县| 含山县| 岐山县| 凤冈县| 天门市| 兰西县| 湟源县| 抚远县| 尼玛县| 新巴尔虎左旗| 广昌县| 酒泉市| 蒙城县| 桑日县| 津南区| 奉化市|