ChemicalBook CAS DataBase List N-METHYLDODECYLAMINE

N-METHYLDODECYLAMINE synthesis

13synthesis methods

Product Name:N-METHYLDODECYLAMINE
CAS Number:7311-30-0
Molecular formula:C13H29N
Molecular Weight:199.38

67-56-1 Synthesis

67-56-1
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$7.29/5ml-f

124-22-1
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$5.00/25g

7311-30-0
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$21.00/250mg

Yield: 86 %Chromat.

Reaction Conditions:

with platinum on carbon;hydrogen;sodium hydroxide at 130; under 30003 Torr; for 24 h;Autoclave;

Steps:

2.4. Typical procedures of catalytic reactions
General procedure: After the reduction under a flow of H₂ at 300°C for 0.5h, we carried out catalytic tests without exposing the catalyst to air as follows. Methanol (30mmol) was injected to the reduced catalyst inside the glass tube through a septum inlet, thus the catalyst was covered with a layer of methanol to restrict it from air exposure. After removal of the septum under air, amine (1mmol), solid NaOH (1mmol), n-dodecane (0.25mmol) and a magnetic stirrer bar were placed in the tube. The tube was inserted into a stainless-steel autoclave (28cm³) and purged with N₂ gas. Finally, the resulting mixture was heated at 150°C and stirred under 1barN₂. For the model reaction of n-octylamine, the catalyst screening, optimization of reaction conditions, kinetic studies and control reactions, the conversion of n-octylamine and yields of products were determined by GC analyses, using n-dodecane as an internal standard by applying the GC sensitivity of the isolated or commercial products. For the substrate scope study, the products were isolated by column chromatography with silica gel 60 (spherical, 60-100μm, Kanto Chemical Co., Ltd.) using hexane/ethyl acetate or ethyl acetate/methanol as the eluting solvent. The yields of the isolated amine derivatives were determined and identified by ¹H and ¹³C NMR and GC-MS methods.

References:

Jamil, Md.A.R.;Touchy, Abeda S.;Rashed, Md. Nurnobi;Ting, Kah Wei;Siddiki, S.M.A. Hakim;Toyao, Takashi;Maeno, Zen;Shimizu, Ken-ichi [Journal of Catalysis,2019,vol. 371,p. 47 - 56]

593-51-1 Synthesis