一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Naphazoline hydrochloride
550-99-2

Naphazoline hydrochloride synthesis

1synthesis methods
-

Yield:550-99-2 92.33%

Reaction Conditions:

with hydrogenchloride in acetonitrile at 20;Large scale;Solvent;

Steps:

1.B-4.B; 1.C-4.C; 1.B-2.B; 1.C-2.C; 3-4
(B) naphazoline free base is dissolved in 8 L of acetonitrile,25% hydrochloric acid was added dropwise at room temperature, pH was adjusted to 2, and a solid was precipitated.The crude product of naphazoline hydrochloride was filtered, 1399.3 g.
(C) The crude product was added to the reaction vessel with 5 L of methanol and heated to 70 ° C.After the solution is dissolved, activated carbon is added, and the temperature is raised to 70 ° C to decolorize.After filtration, 1 L of acetone was added dropwise to the filtrate, the filtrate was cooled and cooled, and the crystal was incubated overnight at 25 ° C.Centrifugation, acetone rinsing, vacuum drying at 50 ° C for about 24 hours to obtain the finished naphazoline hydrochloride,White solid, 1366.6g,The yield was 92.33%, and the purity was 99.90% by HPLC.The bulk density is 0.49g/cm3,The angle of repose is 27°.The powder is loose and weak.

References:

Guangdong Xian Qiang Pharmaceutical Co., Ltd.;Guangdong Zhongsheng Pharmaceutical Co., Ltd.;Guangdong South China Pharmaceutical Group Co., Ltd.;Huang Caifeng;Li Wan;Xiong Weimei;Ye Qiongxian;Tan Zhenyou CN110041261, 2019, A Location in patent:Paragraph 0040; 0043-0044; 0045; 0048-0049; 0050; 0053-0054

FullText

Naphazoline hydrochloride Related Search:

江山市| 宁乡县| 全椒县| 文成县| 五峰| 隆化县| 花莲市| 周口市| 疏附县| 襄汾县| 达日县| 渝中区| 蒙自县| 伊宁县| 南岸区| 嵊泗县| 大厂| 滨州市| 鄂托克前旗| 兰西县| 扎兰屯市| 阳泉市| 麻栗坡县| 邵阳县| 白沙| 安龙县| 济源市| 遂川县| 南宫市| 安丘市| 敖汉旗| 昌都县| 桐乡市| 武陟县| 阿拉尔市| 嫩江县| 成武县| 双柏县| 贵德县| 隆林| 沽源县|