PACLITAXEL C synthesis
- Product Name:PACLITAXEL C
- CAS Number:153415-45-3
- Molecular formula:C46H57NO14
- Molecular Weight:847.94
![Benzenepropanoic acid, α-hydroxy-β-[[(2,2,2-trichloroethoxy)carbonyl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-](/CAS/20211123/GIF/602319-12-0.gif)
602319-12-0
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153415-45-3
87 suppliers
$109.00/50 mg
Yield:-
Steps:
Multi-step reaction with 2 steps
1: 60 percent / zinc; AcOH / ethyl acetate / 8 h
2: 56 percent / 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; 1-hydroxybenzotriazole / dimethylformamide / 3 h / 20 °C
References:
Skwarczynski, Mariusz;Sohma, Youhei;Noguchi, Mayo;Kimura, Maiko;Hayashi, Yoshio;Hamada, Yoshio;Kimura, Tooru;Kiso, Yoshiaki [Journal of Medicinal Chemistry,2005,vol. 48,# 7,p. 2655 - 2666]
133524-70-6
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142-62-1
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153415-45-3
87 suppliers
$109.00/50 mg