Propoxur synthesis
- Product Name:Propoxur
- CAS Number:114-26-1
- Molecular formula:C11H15NO3
- Molecular Weight:209.24
Yield:114-26-1 99%
Reaction Conditions:
with N,N'-dimethylbenzylamine at 60 - 90; for 3 h;Reagent/catalyst;Temperature;
Steps:
1; 2; 3; 4; 5 Example 1
A preparation method of propoxur, which is prepared by using o-isopropoxy phenol and methyl isocyanate as raw materials, and preparing a propoxur under the catalysis of a moderately active amine compound as a catalyst, comprising the following steps:With mechanical agitation,Condenser,In the 250mL four-port reaction bottle of the exhaust receiver,Inject 76 g of o-isopropoxyphenol (content >99%, 0.55 mol) and 0.015 g of N,N-dimethylbenzylamine (content >98%, 0.00011 mol),Adjust the temperature of the heating jacket,The temperature in the reactor rose to 60 ° C.Starting to add 33.28 g of methyl isocyanate (content >99%, 0.58 mol),After the completion of the dropwise addition, the temperature was raised to 90 ° C for 3 h.After the reaction is finished, the material is discharged.After cooling, slice and bag,Obtained 113.85 g of 98.1% by mass of propoxur.The yield is 99.0%,The impurity 266 has a mass percentage of 0.1%.
References:
Hunanhaili Changde Pesticide Chemical Co., Ltd.;Zhou Jinping;Zhou Liang;Zang Yangling;Huang Youyuan;Wang Yan;Zhou Yong CN109384692, 2019, A Location in patent:Paragraph 0021-0034
105-40-8
96 suppliers
$40.00/250mg
4812-20-8
163 suppliers
$6.00/1g
114-26-1
234 suppliers
$25.00/25mg