quinoline-2-carboxiMidaMide hydrochloride synthesis
- Product Name:quinoline-2-carboxiMidaMide hydrochloride
- CAS Number:110177-05-4
- Molecular formula:C10H10ClN3
- Molecular Weight:207.6595
1436-43-7
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Yield:-
Reaction Conditions:
Stage #1: quinoline-2-carbonitrilewith methanol;sodium methylate at 20; for 6 h;Inert atmosphere;
Stage #2: with ammonium chloride in methanol at 20; for 18 h;Inert atmosphere;
References:
Zhang, Nan;Ayral-Kaloustian, Semiramis;Nguyen, Thai;Hernandez, Richard;Lucas, Judy;Discafani, Carolyn;Beyer, Carl [Bioorganic and Medicinal Chemistry,2009,vol. 17,# 1,p. 111 - 118] Location in patent:experimental part