R428 synthesis
- Product Name:R428
- CAS Number:1037624-75-1
- Molecular formula:C30H34N8
- Molecular Weight:506.64
91-13-4
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1037624-75-1
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Yield:-
Steps:
Multi-step reaction with 7 steps
1.1: sodium methylate
2.1: potassium hydroxide / ethanol / 85 °C
3.1: nitric acid; sulfuric acid / nitromethane
4.1: acetic acid; sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane
5.1: hydrogen; palladium on activated charcoal / methanol
6.1: Resolution of racemate
6.2: Alkaline conditions
7.1: isopropyl alcohol
References:
Gras [Drugs of the Future,2018,vol. 43,# 9,p. 645 - 653]
24790-66-7
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1037624-75-1
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37949-03-4
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$27.00/100mg
1037624-75-1
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![2-nitro-8,9-dihydro-5H-benzo[7]annulen-7(6H)-one](/CAS/20180713/GIF/740842-50-6.gif)
740842-50-6
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$200.00/100mg
1037624-75-1
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![1-(2-NITRO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULEN-7-YL)PYRROLIDINE](/CAS/20200611/GIF/1037627-93-2.gif)
1037627-93-2
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1037624-75-1
158 suppliers
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