SULFENTRAZONE synthesis
- Product Name:SULFENTRAZONE
- CAS Number:122836-35-5
- Molecular formula:C11H10Cl2F2N4O3S
- Molecular Weight:387.19
111992-18-8
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16156-53-9
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122836-35-5
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$155.00/1g
Yield:122836-35-5 92%
Reaction Conditions:
Stage #1:2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one with chloro(dimethyl)sulfonium chloride in dichloromethane at 0 - 5; for 0.5 h;
Stage #2:isobutyl methanesulfonate in dichloromethane at 0 - 5; for 10 h;
Steps:
19 Example 3
General procedure: Into a 250ml four-necked flask, 15.6 g (0.05mol) of triazolinone aniline is dissolved in 50g of dichloromethane, cool down at 0-5 ° C, and add the catalyst of Example 1, the mass of dimethyl chloride Chlorosulfur is 5% of the mass of the triazolinone aniline, stir for 30min; after that at this temperature added the drops of Methyl methanesulfonate 6.7g, after completion of the drop-wise addition, the reaction is stirred at this temperature for 3 hours after that the raw materials are basically completely reacted; the reaction solution is cooled at 0 ° C, suction filtered, dried, obtained 19.3 g of Sulfentrazone solid, the content detected by HPLC is 99.1%, yield is 98.8%. Distillation of the mother liquor obtained by filtration, Dichloromethane and methanol were recovered in sections.
References:
Shandong Weifang Runfeng Chemical Co., Ltd.;Sun Guoqing;Hou Yongsheng;Xu Yanlei;Zhao Guangli;Song Xinke CN108424395, 2018, A Location in patent:Paragraph 0029; 0045
66-27-3
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122836-35-5
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$155.00/1g
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1912-31-8
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122836-35-5
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124-63-0
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122836-35-5
160 suppliers
$155.00/1g
111992-18-8
11 suppliers
inquiry
122836-35-5
160 suppliers
$155.00/1g