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ChemicalBook CAS DataBase List Topotecan

Topotecan synthesis

2synthesis methods

7689-03-4 Synthesis

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: H₂; AcOH / PtO₂
1.2: 51 percent / Pb(OAc)4; AcOH
2.1: 65 percent / aq. AcOH

References:

Gao, Mingzhang;Miller, Kathy D.;Sledge, George W.;Zheng, Qi-Huang [Bioorganic and Medicinal Chemistry Letters,2005,vol. 15,# 17,p. 3865 - 3869]

19685-09-7 Synthesis

Etoposide Vinblastine sulfate Mitomycin C Vancomycin Tobramycin TOPOTECANACETATE N-DESMETHYL TOPOTECAN

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