Vanillylacetone synthesis
- Product Name:Vanillylacetone
- CAS Number:122-48-5
- Molecular formula:C11H14O3
- Molecular Weight:194.23
1080-12-2
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$11.00/250mg
122-48-5
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$5.00/50mg
Yield:122-48-5 87%
Reaction Conditions:
with palladium on activated charcoal;hydrogen;acetic acid in ethanol at 20; under 760.051 Torr;
Steps:
1
38.44 g of 4-(4-hydroxy-3-methoxyphenyl)-3-ene-2-butanone was dissolved in 500 mL of ethanol.Add 500 mL of acetic acid with stirring, and add 1.92 g of Pd/C.After the hydrogen balloon was placed, the gas was exchanged three times, and after reacting at room temperature for 1 hour,Filtration, the filtrate was evaporated to ethanol, water was added, and then extracted with ethyl acetate.The liquid phase was separated, and the organic phase was washed with a saturated NaHCO 3 solution and water, respectively.The solvent is removed by pressure reduction and separated by column chromatography.Obtained a colorless liquid of 31.07g,The yield was 87%.
References:
CN108191625,2018,A Location in patent:Paragraph 0029; 0034; 0036
121-33-5
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122-48-5
367 suppliers
$5.00/50mg
1080-12-2
135 suppliers
$11.00/250mg
122-48-5
367 suppliers
$5.00/50mg
39728-80-8
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61152-59-8
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122-48-5
367 suppliers
$5.00/50mg