| Identification | Back Directory | [Name]
Benzamide, 3,4,5-trihydroxy-N-[4-[(4-hydroxybenzoyl)amino]phenyl]- | [CAS]
2489813-08-1 | [Synonyms]
α-Synuclein inhibitor 4
Benzamide, 3,4,5-trihydroxy-N-[4-[(4-hydroxybenzoyl)amino]phenyl]- | [Molecular Formula]
C20H16N2O6 | [MOL File]
2489813-08-1.mol | [Molecular Weight]
380.35 |
| Hazard Information | Back Directory | [Uses]
α-Synuclein inhibitor 4 (compound 3gh) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 0.98 μM and inhibition ratio at 30 μM of 91.2%[1]. | [IC 50]
α-synuclein Aggregation | [References]
[1] Chen L, et al. Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro α-synuclein aggregation. Bioorg Med Chem. 2020 Aug 1;28(15):115596. DOI:10.1016/j.bmc.2020.115596 |
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