| Identification | Back Directory | [Name]
Benzamide, 3,4,5-trihydroxy-N-[4-[[(4-methylphenyl)sulfonyl]amino]phenyl]- | [CAS]
2489813-11-6 | [Synonyms]
α-Synuclein inhibitor 5
Benzamide, 3,4,5-trihydroxy-N-[4-[[(4-methylphenyl)sulfonyl]amino]phenyl]- | [Molecular Formula]
C20H18N2O6S | [MOL File]
2489813-11-6.mol | [Molecular Weight]
414.43 |
| Hazard Information | Back Directory | [Uses]
α-Synuclein inhibitor 5 (compound 4aa) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.22 μM and inhibition ratio at 30 μM of 94.3%[1]. | [IC 50]
α-synuclein Aggregation | [References]
[1] Chen L, et al. Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro α-synuclein aggregation. Bioorg Med Chem. 2020 Aug 1;28(15):115596. DOI:10.1016/j.bmc.2020.115596 |
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