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252039-52-4

252039-52-4 Structure

252039-52-4 Structure
IdentificationBack Directory
[Name]

C18 L-erythro Ceramide (d18:1/18:0)
[CAS]

252039-52-4
[Synonyms]

Octadecanoyl-L-erythro-sphingosine
C18 L-erythro Ceramide (d18:1/18:0)
Octadecanamide, N-[(1R,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
[Molecular Formula]

C36 H71 N O3
[MOL File]

252039-52-4.mol
[Molecular Weight]

565.95
Chemical PropertiesBack Directory
[Boiling point ]

694.5±55.0 °C(Predicted)
[density ]

0.915±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

A solid
[pka]

13.54±0.20(Predicted)
Hazard InformationBack Directory
[Description]

C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide . It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.11 mol% (8.8 μM). [Matreya, LLC. Catalog No. 1850]
[Uses]

Octadecanoyl-L-erythro-sphingosine is an ester product.
[storage]

Store at -20°C
[References]

[1] JULNAR USTA, A. HANNUN  Alicja B. Structural Requirements of Ceramide and Sphingosine Based Inhibitors of Mitochondrial Ceramidase?[J]. Biochemistry Biochemistry, 2001, 40 32: 9657-9668. DOI: 10.1021/bi010535k
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