| Chemical Properties | Back Directory | [Boiling point ]
694.5±55.0 °C(Predicted) | [density ]
0.915±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
A solid | [pka]
13.54±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
C18 D-threo ceramide (d18:1/18:0) is a biochemical reagent. | [Biological Activity]
C18 D-threo Ceramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1 It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 16.6 μM.2 [Matreya, LLC. Catalog No. 1855] | [References]
1.Koolath, S., Murai, Y., Suga, Y., et al.Chiral combinatorial preparation and biological evaluation of unique ceramides for inhibition of sphingomyelin synthaseChirality32(3)308-313(2019)
2.Usta, J., El Bawab, S., Roddy, P., et al.Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidaseBiochemistry40(32)9657-9668(2001)
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ChemeGen
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https://www.chemegen.com |
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