109010-60-8
中文名稱
(S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-乙酸叔丁酯
英文名稱
S-ATBA
CAS
109010-60-8
分子式
C16H22N2O3
MDL 編號
MFCD00895734
分子量
290.36
MOL 文件
109010-60-8.mol
更新日期
2026/07/15 12:22:57
109010-60-8 結(jié)構(gòu)式
基本信息
中文別名
(S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-乙酸叔丁酯{(3S)-3-[(1S)-1-乙氧羰基-3-苯基丙基氨基]-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-基}乙酸單鹽酸鹽
鹽酸貝那普利
鹽酸苯那普利
貝納普利
(S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-乙酸-1,1-二甲基乙酯
(S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并雜卓-1-乙酸叔丁酯
酸貝那普利
3S-氨基-2,3,4,5-四氫-1H-[1]-苯并氮雜卓-2-酮-1-乙酸叔丁酯
英文別名
{(3s)-3-[(1s)-1-ethoxycarbonyl-3-phenylpropylamino]-2,3,4,5-tetrahydro-2-oxo-1h-1-benzazepin-1-yl}acetic acid hydrochloride(3S)-3-[[(1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMINO]-2,3,4,5-TETRAHYDRO-2-OXO-1H-1-BENZAZEPINE-1-A
(3S)-3-[[(1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMINO]-2,3,4,5-TETRAHYDRO-2-OXO-1H-1-BENZAZEPINE-1-ACETIC ACID HYDROCHLORIDE
(3S)-3-AMINO-1-(TERT-BUTYLCARBOXYMETHYL)-2,3,4,5-TETRAHYDRO-1H-BENZAZEPIN-2-ONE
3-(S)-AMINO-1-TERTBUTYLOXYCARBONYLMETHYL-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-2-ONE
BENAZEPRIL HCL
BENAZEPRIL HYDROCHLORIDE
(S)-3-AMINO-1-(TERT-BUTOXYCARBONYLMETHYL)-2,3,4,5-TETRAHYDRO-1H-BENZAZEPIN-2-ONE
(s)-3-amino-2,3,4,5-tetrahydro-2-oxo-1h-1-benazepine-1-acetic acid 1,1-dimethyl ethyl ester
(S)-3-AMINO-2,3,4,5-TETRAHYDRO-2-OXO-1H-1-BENZAZEPINE-1-ACETIC ACID 1,1-DIMETHYL ETHYL ESTER
s-atba
(S)-TERT-BUTYL 2-(3-AMINO-2-OXO-2,3,4,5-TETRAHYDROBENZO[B]AZEPIN-1-YL)ACETATE
T-BUTYL 3-(S)-AMINO-2,3,4,5-TETRAHYDRO-1H-[1]BENZEPINE-2-ONE-1-ACETATE
TERT-BUTYL-3-AMINO-2,3,4,5-TETRAHYDRO-2-OXO-1H-(3S)-BENZAZEPINE-1-ACETATE
TERTBUTYL (3S)-3-AMINO-2,3,4,5-TETRAHYDRO-1H-(1)-BENZAZEPIN-2-ONE-1-ACETATE
TERT-BUTYL-(S)-(3-AMINO-2-OXO-2,3,4,5-TETRAHYDROBENZO[B]AZEPIN-1-YL)ACETATE
(S)-tert-butyl-2-(3-amino-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetate
BNZ
3-(S)-amino-1-tertbutyloxycarbonylmethyl-2,3,4,5-tetrahydro-1H-1-benzazepin-2-on
(S)-3-AMINO-2,3,4,5-TETRAHYDRO-2-OXO-1H-1-BENZAZEPINE-1-ACETATIC ACID-1,1-DIMETHYLETHYL
所屬類別
原料藥：抗高血壓病藥物理化學(xué)性質(zhì)
外觀白色或類白色結(jié)晶性粉末。
熔點(diǎn)115-116°C
比旋光度-270 º (c=0.5, EtOH)
沸點(diǎn)483.2±45.0 °C(Predicted)
密度1.133±0.06 g/cm3(Predicted)
儲存條件Keep in dark place,Inert atmosphere,2-8°C
溶解度DMSO: ~34 mg/mL, soluble
酸度系數(shù)(pKa)7.37±0.20(Predicted)
形態(tài)solid
形態(tài)固體
顏色white
顏色白色
旋光度 (Optical Rotation)Consistent with structure
主要應(yīng)用pharmaceutical (small molecule)
InChIInChI=1S/C16H22N2O3/c1-16(2,3)21-14(19)10-18-13-7-5-4-6-11(13)8-9-12(17)15(18)20/h4-7,12H,8-10,17H2,1-3H3/t12-/m0/s1
InChIKeyQTEDVVHLTMELTB-LBPRGKRZSA-N
SMILESN1(CC(OC(C)(C)C)=O)C2=CC=CC=C2CC[C@H](N)C1=O
CAS 數(shù)據(jù)庫109010-60-8(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H315-H317-H335
安全說明22-24/25
WGK Germany2
RTECS號CX7065000
REACH 注冊登記Active
海關(guān)編碼2933790002
存儲類別11 - Combustible Solids
應(yīng)用領(lǐng)域
用途一
用于新型抗高血壓類藥物血管緊張素轉(zhuǎn)化酶抑制劑（ACE-I）苯那普利（Benazepril）的制造。用途二
109010-60-8（(S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-乙酸叔丁酯）是貝那普利中間體。(S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-乙酸叔丁酯價(jià)格(試劑級)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2026/06/05 | XW0210901060804 | (S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-乙酸叔丁酯 | 109010-60-8 | 25G | 178元 |
| 2026/06/05 | XW0210901060803 | (S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-乙酸叔丁酯 | 109010-60-8 | 10G | 73元 |
| 2026/06/05 | XW0210901060802 | (S)-3-氨基-2,3,4,5-四氫-2-氧-1H-1-苯并氮雜卓-1-乙酸叔丁酯 | 109010-60-8 | 5G | 39元 |