150145-89-4

中文名稱 (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

英文名稱 (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

CAS 150145-89-4

分子式 C10H11NO4

分子量 209.2

MOL 文件 150145-89-4.mol

更新日期 2024/12/03 15:40:34

150145-89-4 結(jié)構(gòu)式

基本信息物理化學(xué)性質(zhì) 安全數(shù)據(jù) (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE價(jià)格(試劑級(jí)) 常見問題列表

基本信息

中文別名

(ALPHAS)-ALPHA-氨基-4-羧基-ALPHA-甲基-苯乙酸

英文別名

(S)-MCPG
(+)-MCPG
(alphaS)-alpha-Amino-4-Carbo
(+)-α-methyl-4-carboxyphenylglycine
(S)-α-Methyl-4-carboxyphenylglycine
(S)-ALFA-METHYL-4-CARBOXYPHENYLGLYCINE
(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
(+)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
4-((1S)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID
(S)-alpha-Methyl-4-carboxyphenylglycine(S)-MCPG

所屬類別

生物化工：甘氨酸類衍生物

物理化學(xué)性質(zhì)

沸點(diǎn)425.3±40.0 °C(Predicted)

密度1.390±0.06 g/cm3(Predicted)

儲(chǔ)存條件Store at RT

溶解度0.1 M NaOH: 15 mg/mL

溶解度0.1MNaOH：15 mg/mL

酸度系數(shù)(pKa)1.76±0.10(Predicted)

形態(tài)solid

顏色白色至灰白色

旋光度 (Optical Rotation)[α]20/D +89.54°, c = 0.33 in 6 M HCl(lit.)

InChI1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)/p-1/t10-/m0/s1

InChIKeyDNCAZYRLRMTVSF-JTQLQIEISA-M

安全數(shù)據(jù)

安全說明24/25

WGK Germany3

海關(guān)編碼29224985

存儲(chǔ)類別11 - Combustible Solids

(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE價(jià)格(試劑級(jí))

報(bào)價(jià)日期	產(chǎn)品編號(hào)	產(chǎn)品名稱	CAS號(hào)	包裝	價(jià)格
2026/06/05	HY-100406	(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE (S)-MCPG	150145-89-4	5mg	800元
2026/06/05	HY-100406	(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE (S)-MCPG	150145-89-4	10mg	1100元
2026/06/05	HY-100406	(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE (S)-MCPG	150145-89-4	25mg	2300元

常見問題列表

生物活性

(S)-MCPG ((+)-MCPG) 是一種有效的 I/II 類代謝型谷氨酸受體 (mGluRs) 拮抗劑，是 (RS)-MCPG (HY-100371) 的活性異構(gòu)體。(S)-MCPG 可用于 mGluRs 在空間學(xué)習(xí)中的作用研究。

靶點(diǎn)

mGluR

體外研究

(S)-MCPG (100 μM) has no detectable effects on basal spine formation or elimination mechanisms in WT slice cultures. (S)-MCPG prevents the increase in spine turnover triggered by TBS and interferes with the mechanisms of activity-dependent spine stabilization in Hippocampal slice cultures.

體內(nèi)研究

MCPG (intraventricular injection; 20 μg) treated rat are slower to learn the task and takes longer to reach the platform than vehicle injected animals. On days 2 and 3, MCPG rats has a significant longer escape latency and the measure of search error is significantly longer on each of the first 3 days. On day 4, MCPG-treated animals reaches the same level of performance as control animals in Morris water maze.