15790-94-0
15790-94-0 結(jié)構(gòu)式
基本信息
反-2-十一烯酸
反-2-十一烯酸, TECH
反-2-十一烯酸,TECH.80%
Undec-2-enoic acid
RARECHEM AL BK 0167
(E)-2-Undecenoic acid
(2E)-2-Undecenoic acid
TRANS-2-UNDECENOIC ACID
trans-undec-2-enoic acid
trans-2-Undecylenic acid
TRANS-2-UNDECENOIC ACID: TECH., 80%
物理化學(xué)性質(zhì)
常見問題列表
反-2-十一烯酸是一種有機中間體，有文獻(xiàn)報道其可由壬醛和膦?；宜峒柞ザ阴ヒ徊椒磻?yīng)制備得到或者由十一烷酸氧化得到。
N2氣氛下，將NaH（油中60％w / w，0.054 mol）懸浮在THF（N2氣氛）中，在5分鐘內(nèi)滴加膦?；宜峒柞ザ阴ィ?4 mmol）。在室溫下繼續(xù)攪拌約2-3分鐘。15分鐘內(nèi)滴加壬醛（49 mmol），繼續(xù)攪拌2 h，用Et2O稀釋溶液，用飽和NaHCO3水溶液和鹽水洗滌，干燥合并的有機萃取液（MgSO4）并蒸發(fā)。用15∶1己烷/ EtOAc在硅膠（5.0×20cm）上通過快速色譜純化殘余物，得到產(chǎn)物反-2-十一烯酸。
The crystal packing of trans-2-Undecenoic acid (E)-undec-2-enoic acid) is described by layers of acid dimers parallel to the (0 4 1) plane which are featured by layers of polar headgroups and hydrophobic hydrocarbon chains. The carboxylic group and the following three carbon atoms (C2, C3, C4) of the trans-2-Undecenoic acid (E)-undec-2-enoic acid) molecule lie in one plane, whereas the atoms of the hydrocarbon chain starting from C4 until C11 adopt a nearly fully staggered conformation.